Semi Prep HPLC Column, RP C4, 10um, 100A. 10mm ID x 50mm Length. Cogent Brand. 1 EA.
Additional Information:
Cogent RP C4 Butyl is a reversed-phase HPLC stationary phase manufactured using high-purity silica with traditional butyl (C4) ligand bonding and complete double endcapping. The moderate hydrophobicity of the C4 ligand makes this stationary phase an excellent choice for purification of hydrophobic and neutral compounds while providing lower retention than C18 phases and greater retention than many C8 phases. The fully endcapped surface delivers reliable chromatographic performance and reproducible purification results for semi-preparative applications.
68004-SP50 is a semi-preparative HPLC column with dimensions of 10 mm ID x 50 mm length, packed with 10 µm RP C4 Butyl particles featuring a 100 Å pore size. The larger internal diameter provides increased sample loading capacity compared to analytical columns, while the short 50 mm length is optimized for rapid purification cycles, method development, and process screening. The 10 µm particle size supports higher flow rates with lower operating backpressure. Typical flow rates are approximately 3–8 mL/min depending on mobile phase conditions, analyte properties, and system capabilities.
This column is intended for semi-preparative HPLC purification where target compounds are isolated and collected for further research, development, formulation, or production. The short column format is particularly useful when throughput and cycle time are prioritized over maximum chromatographic resolution. Applications include pharmaceutical research, synthetic chemistry, natural product purification, reference standard preparation, and process development. A specialized HPLC system capable of semi-preparative flow rates, larger injection volumes, and fraction collection is required. This product is supplied as a Special Order Item manufactured specifically upon receipt of order.
Key Benefits
RP C4 Butyl stationary phase
Fully double endcapped chemistry
Traditional butyl (C4) bonded phase
Designed for semi-preparative HPLC purification
Increased sample loading capacity
10 µm particles for lower operating backpressure
Suitable for higher flow rates
Less retention than C18 columns
Fast purification cycles with 50 mm length
Ideal for method development and process screening
Typical Applications
Semi-preparative HPLC purification
Small molecule isolation
Pharmaceutical research
Synthetic chemistry
Natural product purification
Reference standard preparation
Process development
Method scale-up
Fraction collection
Compound recovery
Specifications
Product Type: Semi-Preparative HPLC Column
Stationary Phase: RP C4 Butyl
Chromatography Mode: Reversed Phase
Bonded Phase: Butyl (C4)
Endcapping: Fully Double Endcapped
Particle Size: 10 µm
Pore Size: 100 Å
Column Dimensions: 10 mm ID x 50 mm
Length: 50 mm
Typical Flow Rate: 3–8 mL/min
Brand: Cogent
Special Order Item Information
Important Notes
Designed for purification rather than routine analytical HPLC
Provides higher loading capacity than analytical columns
Requires a semi-preparative HPLC system capable of appropriate flow rates and fraction collection
Provides less retention than C18 phases and greater retention than many C8 phases
Short column length supports rapid purification and method development workflows
Special Order Item